A general and convenient catalytic synthesis of nitriles from amides and silanes.
نویسندگان
چکیده
A new and convenient protocol for the catalytic dehydration of aromatic and aliphatic amides using silanes in the presence of catalytic amounts of fluoride is presented. The synthesis of aliphatic and aromatic nitriles proceeds with high selectivity under mild conditions. Notably, a wide substrate range is converted in good to excellent yields.
منابع مشابه
Ultrasound Promoted Efficient Synthesis of some Amides from Nitriles in Ambient Condition
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عنوان ژورنال:
- Organic letters
دوره 11 11 شماره
صفحات -
تاریخ انتشار 2009